Download Microvascular Research Biology and Pathology, Two-Volume by David Shepro PDF

By David Shepro

The microvasculature refers back to the smallest blood vessels, arterial and venous, that nurture the tissues of every organ. except shipping, additionally they give a contribution to the systematic rules of the physique. In daily terminology, the microcirculation is "where the motion is." Microcirculation is at once thinking about such sickness states as Alzheimers, irritation, tumor progress, diabetic retinopathy, and wound therapeutic- plus cardiovascular health is without delay concerning the formation of recent capillaries in huge muscle groups. Microvascular Research is the 1st publication dedicated solely to this important systemic element of the cardiovascular approach and gives modern mini-reviews of ordinary features and medical states. The contributing authors are senior scientists with overseas acceptance of their given disciplines.

This two-volume set is a huge, interdisciplinary paintings that encompasses uncomplicated learn and medical functions both.

* large assurance of either uncomplicated and medical facets of microvasculature research
* comprises 167 chapters from over three hundred foreign authors
* every one bankruptcy contains key figures and annotated references

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Additional resources for Microvascular Research Biology and Pathology, Two-Volume Set, Volume 1-2

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Huxley Introduction Forces Regulating Transvascular Water Movement Pathways for Volume Flux across Microvascular Walls Assessment of Transvascular Water Movement in Vivo Regulation of Hydraulic Conductivity Summary Myosin Light-Chain Kinase (MLCK) Protein Kinase C (PKC) cAMP- and cGMP-Dependent Protein Kinases (PKA and PKG) Mitogen-Activated Protein Kinases (MAPKs) Nonreceptor Protein Tyrosine Kinases (PTKs) Summary Section E: Transport, Junctions, Adhesion Molecules CHAPTER 46 CHAPTER 43 The Role of Gap Junctions in the Regulation of Arteriolar Tone CHAPTER 45 Protein Kinases and Microvascular Permeability Role of Pericytes in Blood Flow Regulation Regulation of Pericyte Contractility Effects of Vasoactive Signals on Pericyte Physiology Pericyte Pathobiology Regulation of Microvascular Hydraulic Conductivity 281 Ingrid H.

Konerding Introduction and Definitions Structural Differences between Tumor and Normal Microvasculature Architectural Differences between Normal and Tumor Microvasculature CHAPTER 136 Cutaneous Microcirculation in Patients with Scleroderma 947 Hiran C. Cooray and Margery A. Barrand Introduction Angiogenesis Role of the Microenvironment and Angiogenesis Targeting Angiogenesis in Tumors Tumor Vasculogenesis Conclusion 961 xliv Contents CHAPTER 143 A Metronomic Approach to Antiangiogenesis CHAPTER 147 969 Raffaele Longo and Giampietro Gasparini CHAPTER 144 975 Philipp C.

Modified from reference [15] with permission. 10 PART I Basic Science Figure 5A–C Effects of normal diet (A), high-cholesterol diet alone (B), or in combination with endothelin ETA receptor antagonist treatment (C) on formation and spatial distribution of coronary vasa vasorum in pigs. Concomitant endothelin blockade essentially prevented adventitial neovascularization. From reference [13] with permission. 11 CHAPTER 1 Endothelin in the Microvasculature Figure 5D Coronary artery wall expression of VEGF protein in pigs after 12weeks of highcholesterol diet.

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