By Gaw, Allan; Shepherd, James
Given the ongoing improvement of latest statins and their expanding, helpful use in medical perform and given the significance of medical learn into the atherosclerotic plaque and its position in cardiovascular and endovascular ailments, given the colossal advances in animal and human experiences that experience taken position over the last few years at a progressively expanding velocity, Gaw and Shepherd have selected subject matters on lipids and atherosclerosis, that are of present curiosity for researchers and clinicians alike. for this reason, the necessity for a common updated evaluate of those advances is obvious. Read more...
summary: Given the ongoing improvement of recent statins and their expanding, important use in scientific perform and given the significance of scientific examine into the atherosclerotic plaque and its position in cardiovascular and endovascular illnesses, given the enormous advances in animal and human stories that experience taken position over the last few years at a gradually expanding velocity, Gaw and Shepherd have selected subject matters on lipids and atherosclerosis, that are of present curiosity for researchers and clinicians alike. accordingly, the necessity for a common up to date evaluation of those advances is apparent
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Additional resources for Lipids and atherosclerosis annual 2001
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32 Immunohistochemical studies have demonstrated that T-cells are present in atheromatous plaques. 33 T-cells are of the T-helper type 1 class, characterized by the production of interleukin-2 and interferon gamma (IFN-γ). These factors can alter plaque morphology, and can also upregulate adhesion molecule expression on endothelial cells, and thus recruit more cells to join the inﬂammatory process. It is now generally recognized that the progression and consequences of atherosclerosis are determined by dynamic interactions between inﬂammatory cells recruited in response to subendothelial lipid accumulation and the local reparative ‘wound-healing’ response of surrounding VSMCs.