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By Emery H. Bresnick (Eds.)

Hematopoiesis, the newest quantity within the Current subject matters in Developmental Biology, covers hematopoiesis, with contributions from a global board of authors. Its chapters supply a entire set of experiences overlaying such issues because the law of blood stem mobilephone improvement, epigenetic mechanisms controlling erythropoiesis, and regulatory RNAs/HSCs.

  • Covers the realm of hematopoiesis
  • International board of authors
  • Provides a finished set of stories overlaying such issues as rules of blood stem mobile improvement, epigenetic mechanisms controlling erythropoiesis, and regulatory RNAs/HSCs

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Sample text

Et al. (2006). Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. Cell, 124, 407–421. Kiel, M. , Yilmaz, O. , & Morrison, S. J. (2005). SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell, 121, 1109–1121. , et al. (2010). Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells. Nature Cell Biology, 12, 1046–1056.

This chapter reviews the structure/function of E-box-GATA composite cis-elements, which collectively constitute an important sector of the hematopoietic stem and progenitor cell cistrome. 1. , 2012). , 2012, 2015). As a single cis-element integrates activities of a limited ensemble of regulatory proteins and signals, it provides a unique path to discover important pathways and regulatory networks. While cis-elements reside at distinct gene locations, including promoters, enhancers, and insulators, and there can be both similarities and differences in their functions at these locations, the focus of this review is on enhancer mechanisms.

Hewitt et al. , 1994). , 1994). , 1991). , 2014). , 2013).

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